Complement Dysregulation During the Early Phases of Synucleinopathy
Hina Khan, Mary Gifford, Arash Kordbacheh, Asher Bury, Spencer Panoushek, Allyson Cole-Strauss, Christopher J. Kemp, Kelvin C. Luk, Kathy Steece‐Collier, Nathan C. Kuhn, Nicholas M. Kanaan, Caryl E. Sortwell, Joseph R. Patterson, Matthew J. Benskey
This study shows that synucleinopathy triggers complement activation and dysregulation before neurodegeneration in a rat model and human Parkinson's disease tissue.
Acta Neuropathologica · Jul 20, 2026Peer-reviewedNeuroscience