Author

Cathee Till

Fred Hutch Cancer CenterORCID 0000-0002-6801-8333Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:GWAS / association mapping· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Christopher A. HaimaniD· 2 shared David V. ContiiD· 2 shared Hans G. LiljaiD· 2 shared Ian Murchie ThompsoniD· 2 shared John P. ShelleyiD· 2 shared John S. WitteiD· 2 shared Jonathan D. MosleyiD· 2 shared Kerry Roe SchafferiD· 2 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Christopher A. HaimanORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Genome-wide association study of prostate-specific antigen levels in 392,522 men identifies new loci and improves cross-ancestry prediction

Thomas J. Hoffmann, Rebecca E. Graff, Ravi Madduri, Alex A Rodriguez, Clinton L. Cario, Kun-Jiang Feng, Yu Jiang, Anqi Wang, Robert J. Klein, Brandon L. Pierce, Scott E. Eggener, Tong Lin, William J. Blot, Jirong Long, Louisa B. Goss, , John S. Witte

This study identifies 447 new genetic variants associated with prostate-specific antigen levels across multiple ancestries and shows improved cross-ancestry prediction of PSA, with implications for personalized prostate cancer screening.

medRxiv · Oct 27, 2023 · PreprintGenetic & Genomic Medicine

Genetically Adjusted PSA Levels for Prostate Cancer Screening

Linda Kachuri, Thomas J. Hoffmann, Yu Jiang, Sonja I. Berndt, John P. Shelley, Kerry Roe Schaffer, Mitchell J. Machiela, Neal D. Freedman, Wen‐Yi Huang, Shengchao A. Li, Ryder Easterlin, Phyllis J. Goodman, Cathee Till, Ian Murchie Thompson, Hans G. Lilja, , John S. Witte

This study develops a polygenic score to adjust PSA levels, improving the detection of aggressive prostate cancer while reducing unnecessary biopsies.

Nature Medicine · Jun 1, 2023Peer-reviewedGenetic & Genomic Medicine