Author

Jaime Fernández Arias

Montreal Neurological Institute and HospitalORCID 0000-0002-6810-5920Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:imaging· 1

Frequent Co-Authors

Cécile TissotiD· 2 shared Félix CarbonelliD· 2 shared Gleb BezginiD· 2 shared Jenna StevensoniD· 2 shared Joseph TherriaultiD· 2 shared Lazaro M. Sanchez-RodrigueziD· 2 shared Nesrine RahmouniiD· 2 shared Pedro Rosa‐NetoiD· 2 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Cécile TissotORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintSep 15, 2023

Transcriptomic signatures of Abeta- and tau-induced neuronal dysfunction reveal inflammatory processes at the core of Alzheimer's disease pathophysiology

Lazaro M. Sanchez-Rodriguez, Ahmed Faraz Khan, Quadri Adewale…·Yasser Iturria‐Medina

The paper uses computational models to identify transcriptomic signatures linked to Aβ and tau-induced neuronal dysfunction in Alzheimer's disease, highlighting immune and inflammatory processes.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintFeb 21, 2023

Revealing the combined roles of Aβ and tau in Alzheimer's disease via a pathophysiological activity decoder

Lazaro M. Sanchez-Rodriguez, Gleb Bezgin, Félix Carbonell…·Yasser Iturria‐Medina

The paper develops a personalized brain activity model integrating functional MRI, Aβ, and tau-PET to reveal synergistic effects of Aβ and tau on cognitive impairment and neuronal excitability in Alzheimer's disease.

5 citations

humanimaging

𝕏 PostBluesky