Author
Montreal Neurological Institute and HospitalORCID 0000-0002-7826-4781Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Peter Kunach, Jaime Vaquer‐Alicea, Matthew S. Smith…·Sarah H. Shahmoradian
The paper determines the cryo-EM structure of Alzheimer's disease tau filaments bound by the PET ligand MK-6240, revealing key binding interactions that inform ligand design.
Lazaro M. Sanchez-Rodriguez, Ahmed Faraz Khan, Quadri Adewale…·Yasser Iturria‐Medina
The paper uses computational models to identify transcriptomic signatures linked to Aβ and tau-induced neuronal dysfunction in Alzheimer's disease, highlighting immune and inflammatory processes.
Lazaro M. Sanchez-Rodriguez, Gleb Bezgin, Félix Carbonell…·Yasser Iturria‐Medina
The paper develops a personalized brain activity model integrating functional MRI, Aβ, and tau-PET to reveal synergistic effects of Aβ and tau on cognitive impairment and neuronal excitability in Alzheimer's disease.
Melissa Savard, Tharick Ali Pascoal, Stijn Servaes…·On behalf of for the Frontotemporal Lobar Degeneration Neuroimaging Initiative
This study investigates how long- and short-range white matter fiber depletion contributes to cognitive deficits in fronto-temporal dementia using diffusion MRI and voxel-based morphometry.