Lazaro M. Sanchez-Rodriguez

Molecular and neuropathological determinants of neuronal dysfunction in Alzheimer's disease

This study identifies molecular predictors of neuronal dysfunction in Alzheimer's disease by analyzing E/I imbalance and its relationship with neuropathology.

Translating the Post-Mortem Brain Multi-Omics Molecular Taxonomy of Alzheimer's Dementia to Living Humans

This study translates post-mortem brain multi-omics AD dementia subtypes into blood, MRI, and psychological markers in living individuals.

Transcriptomic signatures of Abeta- and tau-induced neuronal dysfunction reveal inflammatory processes at the core of Alzheimer's disease pathophysiology

The paper uses computational models to identify transcriptomic signatures linked to Aβ and tau-induced neuronal dysfunction in Alzheimer's disease, highlighting immune and inflammatory processes.

Revealing the combined roles of Aβ and tau in Alzheimer's disease via a pathophysiological activity decoder

The paper develops a personalized brain activity model integrating functional MRI, Aβ, and tau-PET to reveal synergistic effects of Aβ and tau on cognitive impairment and neuronal excitability in Alzheimer's disease.

Detecting brain network communities: considering the role of information flow and its different temporal scales

This paper introduces a method to detect brain network communities at different temporal scales by analyzing information flow through oscillatory modes and clustering nodes based on their co-occurrence.

Estimation of Global and Local Complexities of Brain Networks: A Random Walks Approach

The paper introduces a new measure of brain network complexity using random walks and finds that the positive functional connectivity network has higher complexity than other network types.