Author

Stuti Mehta

Boston Children's HospitalORCID 0000-0002-6810-6771Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Assay:Hi-C· 1

Frequent Co-Authors

Stuart H. OrkiniD· 3 shared Allyson Bowker· 1 shared Altantsetseg Buyanbat· 1 shared Andrew V. KossenkoviD· 1 shared Behnam NabetiD· 1 shared Flora Dievenich Braes· 1 shared Ge Zheng· 1 shared Guo‐Cheng YuaniD· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersMolecular Biology

Stuart H. OrkinORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintMar 30, 2023

Matrin3 mediates differentiation through stabilizing chromatin accessibility and chromatin loop-domain interactions, and YY1 mediated enhancer-promoter interactions

Tianxin Liu, Qian Zhu, Kai Yan…·Stuart H. Orkin

The paper shows Matrin3 stabilizes chromatin accessibility and loop-domain interactions, and facilitates YY1-mediated enhancer-promoter interactions during differentiation.

DOI 10.1101/2023.03.30.534959

mouseChIP-seq

Systems BiologybioRxivPreprintMar 13, 2023

Leukemia core transcriptional circuitry is a sparsely interconnected hierarchy stabilized by incoherent feed-forward loops

Taku Harada, Jérémie Kalfon, Monika W. Perez…·Maxim Pimkin

The paper reconstructs a sparsely interconnected transcriptional hierarchy in leukemia cells stabilized by incoherent feed-forward loops and shows inhibitors disrupt core regulators' programs.

7 citations

humanbulk RNA-seq

Molecular BiologybioRxivPreprintMay 2, 2022

High-efficiency HDR in immortalized cell lines by crude rAAV mediated donor template delivery

Stuti Mehta, Altantsetseg Buyanbat, Ge Zheng…·Stuart H. Orkin

This study demonstrates high-efficiency HDR-mediated knock-in of large DNA fragments in human and mouse cell lines using crude rAAV without purification.

3 citations

humanmouse