Structural Insights into the Role of the Proline Rich Region in Tau Function
Karen Acosta, Christopher R. Brue, Polina Holubovska, Hee Jong Kim, Leland C. Mayne, Kenji Murakami, Elizabeth R. Rhoades
This study investigates how phosphomimic mutations in tau's proline-rich region affect tubulin dimer binding and microtubule polymerization.
Structure · Jan 17, 2025Peer-reviewedBiophysics