Author

Hee Jong Kim

University of PennsylvaniaORCID 0000-0002-0823-5301Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Kenji MurakamiiD· 2 shared An XuiD· 1 shared Benjamin A. GarciaiD· 1 shared Christopher R. BrueiD· 1 shared Dung‐Fang LeeiD· 1 shared E. James PeterssoniD· 1 shared Elizabeth R. RhoadesiD· 1 shared Evan S. K. Yanagawa· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersBiophysics

Kenji MurakamiORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Determination of α-Synuclein Protein Interactions by μMap Photo-proximity Labeling

Marshall G. Lougee, Grace S. H. Park, Hee Jong Kim, Jiya Fowler, Zongtao Lin, Hossein Fazelinia, Evan S. K. Yanagawa, Vinayak V. Pagar, Tak Ian Chio, Lynn A. Spruce, Virginia M.‐Y. Lee, Benjamin A. Garcia, Melike Lakadamyali, E. James Petersson

This study uses μMap photo-proximity labeling to compare the interactomes of α-synuclein monomers and fibrils in mouse brain lysate to investigate synucleinopathy mechanisms.

Journal of the American Chemical Society · Apr 8, 2026Peer-reviewedBiochemistry

Structural Insights into the Role of the Proline Rich Region in Tau Function

Karen Acosta, Christopher R. Brue, Polina Holubovska, Hee Jong Kim, Leland C. Mayne, Kenji Murakami, Elizabeth R. Rhoades

This study investigates how phosphomimic mutations in tau's proline-rich region affect tubulin dimer binding and microtubule polymerization.

Structure · Jan 17, 2025Peer-reviewedBiophysics

Structural basis of the human transcriptional Mediator complex modulated by its dissociable Kinase module

Ti‐Chun Chao, Shin-Fu Chen, Hee Jong Kim, Hui-Chi Tang, Hsiang-Ching Tseng, An Xu, Leon Palao, Subash Khadka, Tao Li, Mo-Fan Huang, Dung‐Fang Lee, Kenji Murakami, Thomas Boyer, Kuang‐Lei Tsai

This study presents cryo-EM structures of the human Mediator complex and its CKM module, revealing how the CKM inhibits transcription by blocking Pol II and PIC assembly.

Molecular Cell · Sep 24, 2024Peer-reviewedBiochemistry