Tom A. McAdams

Using twin-pairs to assess potential bias in polygenic prediction of externalising behaviours across development

The paper assesses bias in polygenic prediction of externalising behaviours using twin-pairs, finding minimal rGE bias but less variance prediction for callous-unemotional traits.

Direct and indirect effects of maternal, paternal, and offspring genotypes: Trio-GCTA

The paper introduces Trio-GCTA, a model to separate direct and indirect genetic effects in parent-offspring trios, applied to four phenotypes using real data.

How important are parents in the development of child anxiety and depression? A genomic analysis of parent-offspring trios in the Norwegian Mother Father and Child Cohort Study (MoBa)

This study uses genomic analysis of parent-offspring trios to estimate the genetic nurture effect on child anxiety and depression symptoms at age 8, finding significant influence on depression but not anxiety.

Comparison of adopted and non-adopted individuals reveals gene-environment interplay for education in the UK Biobank

The paper compares polygenic scores for education between adopted and non-adopted individuals in the UK Biobank to assess gene-environment interplay, finding stronger genetic prediction in non-adopted individuals.

Evidence for gene-environment correlation in child feeding: Links between common genetic variation for BMI in children and parental feeding practices

This paper investigates gene-environment correlation by showing that children's genetic predispositions to BMI influence parental feeding practices, with polygenic scores linked to restriction and pressure.