Joanna K. Bright

Comparison of Automated White Matter Lesion Segmentation Approaches for Use in Large, Multi-Site Data Analyses in Parkinson's Disease

This paper evaluates automated white matter lesion segmentation methods in Parkinson's disease and healthy controls, finding U-Net-pgs to be the most accurate and reliable approach across multiple metrics and datasets.

Using twin-pairs to assess potential bias in polygenic prediction of externalising behaviours across development

The paper assesses bias in polygenic prediction of externalising behaviours using twin-pairs, finding minimal rGE bias but less variance prediction for callous-unemotional traits.

Sex-Dependent Age Trajectories of Subcortical Brain Structures: Analysis of Large-Scale Percentile Models and Shape Morphometry

The paper creates normative percentile charts for subcortical brain volumes across adulthood and examines age-by-sex interactions and associations with APOE genotype in a large UK Biobank sample.

Age-dependent genetic variants associated with longitudinal changes in brain structure across the lifespan

This study identifies genetic variants linked to longitudinal brain structure changes across the lifespan using MRI data from 15,640 individuals.

Hippocampal subfield volumes are uniquely affected in PTSD and depression: International analysis of 31 cohorts from the PGC-ENIGMA PTSD Working Group

This study identifies hippocampal subfield volume differences in PTSD and depression across 31 cohorts, finding depression has a stronger effect than PTSD, especially in CA1, with comorbid cases showing more pronounced changes.