BiochemistryComputational and Structural Biotechnology JournalPeer-reviewed
Cryo-EM Structure of AAA + ATPase Thorase Reveals Novel Helical Filament Formation
Mohammad Aasif Dar, Robert K. Louder, Marisol Cortés…·Valina Lynn Dawson
The paper determines the cryo-EM structure of Thorase filaments, showing how ATP binding drives filament formation and provides insights into its role in disassembling mTORC1 complexes.
DOI 10.1016/j.csbj.2025.05.018