Author

Ajeena Ramanujan

National University of SingaporeORCID 0000-0002-6843-5372Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2

Frequent Co-Authors

Carlos F. IbáñeziD· 3 shared Chenju YiiD· 1 shared Kazuhiro TanakaiD· 1 shared Ket Yin GohiD· 1 shared Lik‐Wei WongiD· 1 shared Meng XieiD· 1 shared Sreedharan SajikumariD· 1 shared Xuetong LiiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersNeuroscience

Carlos F. IbáñezORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintFeb 11, 2026

Coupling of death receptor p75NTR to the RhoA and NF-kB pathways differentially regulates internalization in hippocampal and cerebellar neurons

Xuetong Li, Ziyi Feng, Ajeena Ramanujan…·Carlos F. Ibáñez

This study shows that p75NTR internalization differs between hippocampal and cerebellar neurons, regulated by distinct signaling pathways involving RhoA and NF-kB.

2 citations

mouseexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintOct 13, 2023

RhoGDI phosphorylation by PKC regulates its interaction with death receptor p75NTR to gate axon growth and neuron survival pathways

Ajeena Ramanujan, Zhen Li, Zhi Lin, Carlos F. Ibáñez

The paper shows how ligand-directed competition between RIP2 and RhoGDI for p75NTR engagement determines axon growth and neuron survival.

DOI 10.1101/2023.10.13.562155

experimental assay

𝕏 PostBluesky

NeuroscienceThe EMBO JournalPeer-reviewedDec 1, 2020

Inactive variants of death receptor p75NTR reduce Alzheimer's neuropathology by interfering with APP internalization

Chenju Yi, Ket Yin Goh, Lik‐Wei Wong…·Carlos F. Ibáñez

The paper shows that inactive p75NTR variants reduce Alzheimer's neuropathology by decreasing APP internalization and amyloidogenic processing in 5xFAD mice.

23 citations

mouseexperimental assay

𝕏 PostBluesky