Author

Megan L. Littlehale

Massachusetts Institute of TechnologyORCID 0000-0002-6848-5687Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Organism:yeast· 1

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John F. MarkoiD· 1 shared Michael T. LaubiD· 1 shared Monica S. GuoiD· 1 shared Ryo Kawamura· 1 shared

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2021-2021 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperMolecular Biology

John F. MarkoORCID

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1 paper

Recent·Most cited

Molecular BiologyeLifePeer-reviewedJul 19, 2021

High-resolution, genome-wide mapping of positive supercoiling in chromosomes

Monica S. Guo, Ryo Kawamura, Megan L. Littlehale…·Michael T. Laub

The paper introduces GapR-seq, a method to map positive supercoiling in genomes, and finds it widespread, associated with transcription and specific genomic features in E. coli and yeast.

83 citationstop 3%

E. coliyeast

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