ImmunologyJournal of Allergy and Clinical ImmunologyPeer-reviewed
BCR ligation selectively inhibits IgE class switch recombination
Adam Kevin Wade-Vallance, Zhiyong Yang, Jeremy B. Libang…·Christopher D.C. Allen
This study shows that BCR ligation selectively inhibits IgE class switch recombination in mouse and human B cells, with synergistic effects from IL-21 and TGFβ1.