Nicholas A. Kotov

MICAL-Inspired Chiral Vanadate Nanoclusters Decelerate Actin Dynamics in Live Cells

This paper introduces chiral vanadate nanoclusters that modulate actin dynamics in live cells by oxidizing specific methionine residues, offering a biocompatible alternative to MICAL enzymes.

Enantiomer-Dependent Biological Activity of Cysteine-Coated Ceria Nanoparticles in Colorectal Cancer Cells

This study shows D-cysteine-coated cerium oxide nanoparticles have stronger anticancer effects than L-cysteine-coated ones in colorectal cancer cells.

Fourier Helicity Spectra as Quantifiers of Multiscale Chirality

This paper introduces Fourier Helicity Spectra to quantify multiscale chirality in 3D structures, demonstrating its application across chemical and biological systems.

Complexes between Netrin G Ligands and Chiral Nanoparticles Promote Axons Regeneration under Near-Infrared Illumination

This study shows that glutathione-coated Ni(OH)2 nanoparticles form complexes with NGL-1, promoting axon regeneration in Alzheimer's and spinal cord-injured mice under near-infrared light.

Struct2Graph: A graph attention network for structure based predictions of protein-protein interactions

Struct2Graph predicts protein-protein interactions using 3D structural data with high accuracy and identifies key residues involved in interactions.