Omri Wurtzel

This study shows that sustained immune activation suppresses planarian regeneration by delaying regenerative progression and causing tissue lysis.

The paper demonstrates that planarians can maintain long-term heritable gene silencing through a two-phase RNAi mechanism independent of canonical RdRPs.

The paper maps single-nucleotide m6A modifications in planarians and shows that multiple YTHDF readers redundantly regulate progenitor fate and body size.

The paper develops a computational model to understand how neoblasts in planarians make stochastic cell-intrinsic decisions to control colony growth and lineage differentiation.

This paper develops a method to isolate live cells from the regenerative tunicate Polycarpa mytiligera, enabling functional analyses and gene expression studies.

This study characterizes the transcriptomic and cellular dynamics of whole CNS regeneration in the tunicate Polycarpa mytiligera, identifying key pathways and markers involved in the process.

PLANAtools provides an interactive repository for analyzing planarian gene expression data from over 160 studies, enabling users to generate plots and annotations without requiring advanced computational expertise.

This study shows that m6A modification is essential for planarian stem cell differentiation and tissue regeneration by regulating histone variant transcription and chromatin modifications.