Author

Marcus R. Breese

Indiana University IndianapolisORCID 0000-0002-6870-0228Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Aafrin M. PettiwalaiD· 1 shared Alejandro Sweet-CorderoiD· 1 shared Alex Gia LeeiD· 1 shared Alexis J. CombesiD· 1 shared Changyong GuoiD· 1 shared Christina M. SheeriniD· 1 shared Christine A. Johnson· 1 shared Clare L. AbramiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Aafrin M. PettiwalaORCID

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2 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintJul 6, 2026

Toward Clinical Implementation of Polygenic Scores for Substance Use Disorders: A Multi-Ancestry Study

Dongbing Lai, Michael Zhang, Tae-Hwi Linus Schwantes-An…·Yunlong Liu

The paper develops and validates polygenic scores for substance use disorders across multiple ancestries, finding clinically relevant performance in European and Latinx populations but not in African populations.

DOI 10.64898/2026.07.03.26357210

humanGWAS summary statistics

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Cancer BiologybioRxivPreprintOct 24, 2025

STING activation reshapes the tumor microenvironment leading to tumor regression in osteosarcoma

Elizabeth P. Young, Christine A. Johnson, Alex Gia Lee…·Alejandro Sweet-Cordero

This study shows that activating the STING pathway in osteosarcoma leads to tumor regression and immune memory, suggesting it as a therapeutic target.

2 citations

humanbulk RNA-seq

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