Author

Aafrin M. Pettiwala

University of California, San FranciscoORCID 0000-0001-9182-7940Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Alejandro Sweet-CorderoiD· 1 shared Alex Gia LeeiD· 1 shared Alexis J. CombesiD· 1 shared Christine A. Johnson· 1 shared Clare L. AbramiD· 1 shared Clifford A. LowelliD· 1 shared Courtney R. SchottiD· 1 shared Douglass Morris· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alejandro Sweet-CorderoORCID

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1 paper

Recent·Most cited

STING activation reshapes the tumor microenvironment leading to tumor regression in osteosarcoma

Elizabeth P. Young, Christine A. Johnson, Alex Gia Lee, Douglass Morris, Jessica L. Tsui, Marcus R. Breese, Juan A. Cámara, Courtney R. Schott, Clare L. Abram, Stanley G. Leung, Leanne C. Sayles, Aafrin M. Pettiwala, Vanessa S. Gutierrez Vera, Clifford A. Lowell, Alexis J. Combes, , Alejandro Sweet-Cordero

This study shows that activating the STING pathway in osteosarcoma leads to tumor regression and immune memory, suggesting it as a therapeutic target.

bioRxiv · Oct 24, 2025 · PreprintCancer Biology