Author

Laurens H. J. Krah

Utrecht UniversityORCID 0000-0002-6879-3962Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Organism:bacteria (other)· 1 Organism:E. coli· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

Rutger HermseniD· 2 shared Benjamin D. TowbiniD· 1 shared Istvan T. KleijniD· 1 shared Martijn WehrensiD· 1 shared Sander J. TansiD· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 7 mutual co-author links

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2 shared papersSystems Biology

Rutger HermsenORCID

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2 papers

Recent·Most cited

Systems BiologybioRxivPreprintAug 29, 2022

The interplay between metabolic stochasticity and regulation in single E. coli cells

Martijn Wehrens, Laurens H. J. Krah, Benjamin D. Towbin…·Sander J. Tans

The paper shows E. coli cells use the cAMP-CRP system to continuously adjust catabolic enzyme expression in response to metabolic fluctuations, revealing noise propagation modes and their regulation.

DOI 10.1101/2022.08.29.505271

E. colistatistical model

𝕏 PostBluesky

Systems BiologyPLoS Computational BiologyPeer-reviewedOct 5, 2018

Noise propagation in an integrated model of bacterial gene expression and growth

Istvan T. Kleijn, Laurens H. J. Krah, Rutger Hermsen

The paper develops a mathematical model of bacterial gene expression and growth, showing how expression noise propagates through metabolic and growth processes and agrees with experimental data.

22 citations

bacteria (other)proteomics

𝕏 PostBluesky