Rutger Hermsen

This paper introduces a fluid-derived lattice method to model bacterial colony growth, reducing artifacts from regular lattices and enabling efficient simulations of large populations.

The paper shows E. coli cells use the cAMP-CRP system to continuously adjust catabolic enzyme expression in response to metabolic fluctuations, revealing noise propagation modes and their regulation.

The paper identifies over 100,000 horizontal gene transfer events across 90,000 bacterial genomes, revealing frequent long-distance genetic exchange and its functional impact.

The paper develops a mathematical model of bacterial gene expression and growth, showing how expression noise propagates through metabolic and growth processes and agrees with experimental data.

This study examines how DNA oxidation affects mutation rates in genomic sequences across different timescales, finding that long Gn tracks experience significantly higher G→T transversion rates.