Benjamin D. Towbin

ALIGN provides a modular framework for analyzing longitudinal development in C. elegans, enabling accurate segmentation, quality control, and motion correction across imaging conditions.

This study shows that reproductive timing is preserved under stress through dynamic control of gonadal growth in C. elegans, maintaining reproductive-to-somatic size ratios.

The paper identifies VHP-1 as a buffer against pharynx-to-body growth imbalance in C. elegans by showing its role in modulating MAPK pathways under tissue-specific growth perturbations.

This study identifies VRK-1 as a regulator of chromatin-nuclear lamina interactions in C. elegans, showing its role in stress-induced chromatin reorganization and survival.

The paper identifies cohesin-dependent 3D chromatin structures called fountains around active enhancers in C. elegans, showing their role in repressing enhancer activity and linking genome architecture to behavior.

RealTrace is a Bayesian method that removes measurement noise from time-lapse microscopy data to reveal biological dynamics, showing fluctuating growth rates and gene expression in single cells.

The paper shows that maternal dietary restriction reduces offspring ribosome content in C. elegans, mediated by mTORC1 signaling, delaying growth until ribosomal levels recover.

This paper introduces a low-cost microfabrication method using 3D printing and repurposed microscopes for biological applications, achieving micrometer precision without clean room infrastructure.

This study shows that autophagy-dependent loss of ribosomal proteins during starvation in C. elegans balances survival and recovery speed by affecting growth resumption.

The paper shows that YAP-1 coordinates organ growth with body size in C. elegans to maintain uniform proportions, even under tissue-specific growth inhibition.

The paper shows E. coli cells use the cAMP-CRP system to continuously adjust catabolic enzyme expression in response to metabolic fluctuations, revealing noise propagation modes and their regulation.

The paper identifies a mechanism in C. elegans that maintains size uniformity by coupling growth rate and developmental duration through an oscillator.

The paper derives and tests a growth law for bacterial upshifts, showing that post-shift growth rate is the geometric mean of pre-shift growth and saturating carbon growth, supported by experiments and theoretical analysis.