Genetic variation at mouse and human ribosomal DNA influences associated epigenetic states
Francisco Rodríguez-Algarra, Robert A. E. Seaborne, Amy F. Danson, Selin Yildizoglu, Harunori Yoshikawa, Pui Pik Law, Zakaryya Ahmad, Victoria A. Maudsley, Ama Brew, Nadine Holmes, Mateus Ochôa, Alan Hodgkinson, Sarah J. Marzi, Madapura M. Pradeepa, Matthew Loose, , Vardhman K. Rakyan
This study shows that genetic variation in rDNA affects epigenetic states and rRNA expression in mice and humans, with species-specific patterns observed.
Genome biology · Feb 14, 2022Peer-reviewedGenomics