Michelle L. Holland

N6-methyladenosine (m6A) RNA modifications control the antiviral response to influenza A virus infection by limiting IFITM2/3 expression

This study shows that m6A RNA modifications regulate antiviral gene expression by limiting IFITM2/3 expression during influenza A virus infection.

Ribosomal DNA copy number is associated with body mass in humans and other mammals

The paper identifies an association between ribosomal DNA copy number and body mass in humans and rats, showing it relates to growth rate and BMI but not obesity.

Genetic variation at mouse and human ribosomal DNA influences associated epigenetic states

This study shows that genetic variation in rDNA affects epigenetic states and rRNA expression in mice and humans, with species-specific patterns observed.

DNA methylation covariation in human whole blood and sperm: implications for studies of intergenerational epigenetic effects

The paper examines DNA methylation differences between human blood and sperm, finding limited correlation and no significant obesity-related changes in sperm methylation.

Identification of MAZ as a novel transcription factor regulating erythropoiesis

This study identifies MAZ as a novel transcription factor regulating erythropoiesis by binding to the -globin gene promoter and interacting with GATA1-bound enhancers, with knockdown impairing differentiation and genetic variants linked to erythroid traits.