Author

Stewart I. Head

Murdoch Children's Research InstituteORCID 0000-0002-6891-7590Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:phylogenetics / evolution· 1 Approach:statistical model· 1

Frequent Co-Authors

Kathryn N. NorthiD· 2 shared Leonit KiriaeviD· 2 shared Peter J. HouwelingiD· 2 shared Adrián Castillo‐GarcíaiD· 1 shared Alejandro LucíaiD· 1 shared Chrystal F. Tiong· 1 shared David R. ThorburniD· 1 shared Håkan WesterbladiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

Kathryn N. NorthORCID

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2 papers

Recent·Most cited

alpha-Actinin-3 deficiency protects from the effects of acute cold exposure through altered skeletal muscle Ca2+ and OXPHOS signaling.

Peter J. Houweling, Chrystal F. Tiong, Leonit Kiriaev, Roberto Díaz‐Peña, Patrick K. Albers, Harrison D. Wood, Victoria L. Wyckelsma, Tegan L. Stait, Tomas Venckūnas, Pedro L. Valenzuela, Adrián Castillo‐García, Marius Brazaitis, Yemima D. Berman, Jane T. Seto, Håkan Westerblad, , Kathryn N. North

This study shows that alpha-actinin-3 deficiency improves cold tolerance through enhanced mitochondrial function and reduced muscle mass loss during acute cold exposure.

bioRxiv · Aug 14, 2024 · PreprintCell Biology

Loss of α-actinin-3 confers protection from eccentric contraction damage in fast-twitch EDL muscles from aged mdx dystrophic mice by reducing pathological fibre branching

Leonit Kiriaev, Peter J. Houweling, Kathryn N. North, Stewart I. Head

The study shows that loss of α-actinin-3 in aged mdx dystrophic mice reduces fibre branching and protects against eccentric contraction damage.

Human Molecular Genetics · Nov 5, 2021Peer-reviewedGenetics