Author

Dosh Whye

Boston Children's HospitalORCID 0000-0002-6895-9627Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1

Frequent Co-Authors

Elizabeth D. ButtermoreiD· 3 shared Gayathri Rajaram SrinivasaniD· 2 shared Mustafa SahiniD· 2 shared Alessandro RosaiD· 1 shared Alessio ColantoniiD· 1 shared Alexandra N. BogomazovaiD· 1 shared Ashish JainiD· 1 shared Ci-Di CheniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersNeuroscience

Elizabeth D. ButtermoreORCID

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3 papers

Recent·Most cited

NeuroscienceAdvanced SciencePeer-reviewedMar 9, 2026

An open-source pipeline for calcium imaging and all-optical physiology in human stem cell-derived neurons

Wardiya Afshar Saber, Federico M. Gasparoli, Ziqin Yang…·Mustafa Sahin

The paper introduces an open-source pipeline for calcium imaging and all-optical physiology in human stem cell-derived neurons, validated for disease modeling and therapeutic screening.

2 citations

humanimaging

NeuroscienceNeurobiology of DiseasePeer-reviewedSep 8, 2025

Excitatory Cortical Neurons from CDKL5 Deficiency Disorder Patient-Derived Organoids Show Early Hyperexcitability Not Identified in Neurogenin2 Induced Neurons

Madison R. Glass, Dosh Whye, Nickesha Camille Anderson…·Mustafa Şahin

This study compares neuronal activity and gene expression in CDD patient-derived neurons from two differentiation methods, finding early hyperexcitability in organoid-derived neurons but not induced neurons.

8 citationstop 4%

humanbulk RNA-seq

NeuroscienceHeliyonPeer-reviewedFeb 21, 2024

Cortical neurons obtained from patient-derived iPSCs with GNAO1 p.G203R variant show altered differentiation and functional properties

Maria Cristina Benedetti, Tiziano D’Andrea, Alessio Colantoni…·Alessandro Rosa

This study uses patient-derived iPSCs with a GNAO1 variant to show altered neuronal differentiation and function in cortical neurons.

19 citations

humanbulk RNA-seq