Author

Charles Lam

University of California, San FranciscoORCID 0000-0002-6897-2549Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Animal Behavior & Cognition· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:behavioral assay· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Allan I. BasbaumiD· 1 shared Chelsea S. BahneyiD· 1 shared Christina A. CapobiancoiD· 1 shared Dane R.G. LindiD· 1 shared Daniel C. JenkinsiD· 1 shared Dustin M. SnapperiD· 1 shared Jacob D. Matityahu· 1 shared Jaimo AhniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperAnimal Behavior & Cognition

Allan I. BasbaumORCID

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2 papers

Recent·Most cited

Deep behavioral phenotyping tracks functional recovery following tibia fracture in mice

Jonathan E. Layne, Dustin M. Snapper, Molly E. Czachor, Charles Lam, Jacob D. Matityahu, Dane R.G. Lind, Matthieu Huard, Johnny Huard, Kazuhito Morioka, Julian C. Motzkin, Allan I. Basbaum, Jarret A.P. Weinrich, Chelsea S. Bahney

This paper develops a machine learning-based behavioral phenotyping approach to quantify functional recovery in mice with tibia fractures, finding that pin stabilization improves recovery and that recovery patterns vary over time.

Frontiers in Physiology · Aug 26, 2025Peer-reviewedAnimal Behavior & Cognition

CD47 is Required for Mesenchymal Progenitor Proliferation and Fracture Repair

Robert L. Zondervan, Christina A. Capobianco, Daniel C. Jenkins, John D. Reicha, Livia M. Fredrick, Charles Lam, Jeanna T. Schmanski, Jeffery S. Isenberg, Jaimo Ahn, Ralph Marcucio, Kurt David Hankenson

This study shows that CD47 inhibition impairs bone fracture healing by reducing mesenchymal stem cell proliferation, despite increased endothelial cell proliferation.

Bone Research · Mar 2, 2025Peer-reviewedMolecular Biology