This study investigates lignin degradation mechanisms in Rhodopseudomonas palustris using multi-omics and CRISPRi to identify essential pathways and improve sustainable valorization of lignin.

Applied and Environmental Microbiology · Jul 8, 2025Peer-reviewedBioengineering

Lipid Metabolism and Contact Site Homologs Are Enriched at the Chloroplast Envelope-Thylakoid Interface

Evan LaBrant, Cailin N. Smith, Alondra D. Torres-Gerena, Joslin Ishimwe, Huang Fan, Allan Tullis, Lauren Litterer, Bhoomi Modi, Michael J. Naldrett, Bara Altartouri, Rebecca Roston

The paper identifies lipid metabolism and contact site homologs enriched at the chloroplast envelope-thylakoid interface, revealing their role in maintaining membrane architecture.

bioRxiv · Jun 20, 2025 · PreprintBiochemistry

Fluorescence based live cell imaging identifies exon 14 skipped hepatocyte growth factor receptor (MET) degraders

Jayapal Reddy Mallareddy, Lin Yang, Wan‐Hsin Lin, Ryan W. Feathers, Jennifer R. Ayers-Ringler, Ezequiel J. Tolosa, Amritha G. Kizhake, Smitha Kizhake, Sydney P. Kubica, Lidia Boghean, Sophie Alvarez, Michael J. Naldrett, Sarbjit Singh, Sandeep Rana, Muhammad Zahid, , Aaron Scott Mansfield

The paper identifies a potent MET degrader using live cell imaging, showing it is more effective than existing PROTACs.

RSC Advances · Jan 1, 2025Peer-reviewedCancer Biology