Fluorescence based live cell imaging identifies exon 14 skipped hepatocyte growth factor receptor (MET) degraders
Jayapal Reddy Mallareddy, Lin Yang, Wan‐Hsin Lin, Ryan W. Feathers, Jennifer R. Ayers-Ringler, Ezequiel J. Tolosa, Amritha G. Kizhake, Smitha Kizhake, Sydney P. Kubica, Lidia Boghean, Sophie Alvarez, Michael J. Naldrett, Sarbjit Singh, Sandeep Rana, Muhammad Zahid, , Aaron Scott Mansfield
The paper identifies a potent MET degrader using live cell imaging, showing it is more effective than existing PROTACs.
RSC Advances · Jan 1, 2025Peer-reviewedCancer Biology