Proton selective conductance and gating of lysosomal cation channel TMEM175
Tobias Schulze, Timon Sprave, Carolin Groebe, Jan H. Krumbach, Magnus Behringer, Kay Hamacher, Gerhard Thiel, Christian M. Grimm, Oliver Rauh
This study investigates the proton selectivity and gating mechanism of the lysosomal cation channel TMEM175 using electrophysiology and molecular dynamics simulations.
bioRxiv · Nov 1, 2024Biophysics