Murat Cirit

This study develops a multi-tissue chip platform to predict human pharmacokinetic parameters of drugs without animal testing, showing accurate correlation with clinical data.

This paper introduces PBSM, a method to quantify transcriptomic similarity between human tissues and preclinical models using RNA-seq and pathway data, showing its application in liver and cardiac tissues.

This study uses a human liver tissue chip to assess drug-drug interactions by evaluating perpetrator and victim drug metabolism over 4 weeks.