Single-cell Transcriptome Profiling of Post-treatment and Treatment-naive Colorectal Cancer: Insights into Putative Mechanisms of Chemoresistance
Г. А. Пузанов, Clémence Astier, Dimitris Papakonstantinou, Mariana Quiroga Londoño, Camille Blériot, Andrey A. Yurchenko, Mohamed Amine Bani, Gérôme Jules-Clément, Fabrice André, Aurélien Marabelle, Antoine Hollebecque, Sergey I. Nikolaev
This study uses scRNA-seq to compare treatment-naive and post-treatment colorectal cancer samples, identifying markers and cell types associated with chemoresistance and response.
Cancer Letters · Nov 9, 2025Peer-reviewedCancer Biology