Author

Juliet Goldsmith

Aligning Science Across Parkinson'sORCID 0000-0002-6935-1744Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

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Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Erika L.F. HolzbauriD· 2 shared Alban OrdureauiD· 1 shared C. Alexander BoeckeriD· 1 shared J. Wade HarperiD· 1 shared Jacob PopolowiD· 1 shared Madeleine Arany· 1 shared Sierra D. PalumbosiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 13 mutual co-author links

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2 shared papersNeuroscience

Erika L.F. HolzbaurORCID

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2 papers

Recent·Most cited

Autophagic stress activates distinct compensatory secretory pathways in neurons

Sierra D. Palumbos, Jacob Popolow, Juliet Goldsmith, Erika L.F. Holzbaur

The paper shows that neurons with Parkinson's disease-associated LRRK2 mutations increase secretion of autophagosomes and exosomes to manage cellular waste and communication, potentially delaying disease onset but contributing to neuroinflammation.

Proceedings of the National Academy of Sciences · Jul 7, 2025Peer-reviewedNeuroscience

Proteomics analysis of autophagy cargos reveals distinct adaptations in PINK1 and LRRK2 models of Parkinson disease

Juliet Goldsmith, Alban Ordureau, C. Alexander Boecker, Madeleine Arany, J. Wade Harper, Erika L.F. Holzbaur

The paper uses proteomics to compare autophagy cargos in two Parkinson disease mouse models, finding distinct adaptive pathways in PINK1 and LRRK2 models.

bioRxiv · Oct 3, 2022 · PreprintMolecular Biology