Braveen B. Joseph

This paper identifies ADM-2 as a negative regulator of molting in C. elegans, showing it inhibits molting by regulating LRP-1 and endocytic trafficking.

The paper shows that transitioning through the L2d stage can rescue molting defects in C. elegans with reduced NEKL function by restoring transcriptional defects associated with molting.

The paper introduces the Sibling Subtraction Method (SSM) to identify causal mutations in C. elegans using whole-genome sequencing, showing it reduces candidate mutations effectively.