Sam E. Williams

The paper identifies a plasmid, pTP33, unique to Second Pandemic Yersinia pestis strains, which may have increased transmission and mortality during that pandemic.

RetroMol converts natural product structures and biosynthetic gene clusters into shared primary sequences to enable biosynthetic similarity comparisons.

The paper reports the discovery of maramycin, a novel isoquinolinequinone alkaloid produced through heterologous expression of a bifunctional enzyme in Streptomyces albidoflavus, showing moderate cytotoxicity against prostate cancer cells.

This paper isolates a new Streptomyces species from a deep-sea sponge and identifies six unique biosynthetic gene clusters through comparative analysis.