BiochemistrybioRxiv
Unfolded Von Willebrand Factor Binds Protein S and Reduces Anticoagulant Activity
Martha M. S. Sim, Molly Y. Mollica, Hammodah R. Alfar…·Jeremy P. Wood
This paper identifies a shear-dependent interaction between Protein S and von Willebrand Factor that reduces free PS anticoagulant activity and contributes to thrombotic risk in viral infections.
DOI 10.1016/j.bvth.2024.100030