Identifying cell type specific driver genes in autism-associated copy number loci from cerebral organoids
Elaine T. Lim, Yingleong Chan, Pepper Dawes, Xiaoge Guo, Serkan Erdin, Derek J.C. Tai, Songlei Liu, Julia M. Reichert, Mannix J. Burns, Ying Chan, Jessica J. Chiang, Katharina Meyer, Xiaochang Zhang, Christopher A. Walsh, Bruce A. Yankner, , George McDonald Church
The paper identifies cell type specific driver genes in autism-associated copy number loci using cerebral organoids and validates findings with CRISPR/Cas9-edited mosaic organoids.
Nature Communications · Jun 10, 2022Peer-reviewedGenomics