Author

Alexandra Karagiaridi

Northwestern UniversityORCID 0000-0002-7003-3233Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Assay:protein structure· 1

Frequent Co-Authors

Benoı̂t RouxiD· 1 shared Heather W. PinkettiD· 1 shared Muyuan CheniD· 1 shared Ramon Mendoza UriarteiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperBiochemistry

Benoı̂t RouxORCID

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1 paper

Recent·Most cited

Nucleotide State Regulates Asymmetric Substrate-Binding Protein Docking in a Type II ABC Importer

Alexandra Karagiaridi, Ramon Mendoza Uriarte, Muyuan Chen, Benoı̂t Roux, Heather W. Pinkett

This study determines the structural changes in a Type II ABC importer's substrate-binding protein in different nucleotide states, revealing how ATP binding and hydrolysis regulate its conformation and interaction with the transporter.

bioRxiv · Oct 16, 2026 · PreprintBiochemistry