RIF1 acts in DNA repair through phosphopeptide recognition of 53BP1
Dheva Setiaputra, Cristina Escribano‐Diaz, Julia K. Reinert, Pooja Sadana, Dali Zong, Elsa Callén, Chérine Sifri, Jan Seebacher, André Nussenzweig, Nicolas H. Thomä, Daniel Durocher
This study identifies RIF1 as a phosphopeptide-binding protein that interacts with phosphorylated 53BP1 epitopes to facilitate DNA repair and modulate shieldin recruitment.
Molecular Cell · Feb 24, 2022Peer-reviewedMolecular Biology