Jan Seebacher

The paper identifies MEP-1 as a novel substrate of DPF-3, showing cleavage after threonine and demonstrating its impact on reproductive fitness.

This study identifies novel components of the aggresome and characterizes their interactions during aggresome processing pathway dynamics in HeLa cells.

The paper develops an in vitro model of human first-trimester trophoblast organoids to study syncytiotrophoblast regeneration after damage and identifies TNFRSF12A as a potential enhancer of this process.

The paper creates a comprehensive atlas of transcription factor interactions in S. pombe using experimental methods and introduces a web tool for exploring the data.

einprot provides an R package for reproducible analysis of quantitative proteomics data, generating reports with interactive visualizations and customizable workflows.

The paper identifies TRIM71's mechanism of mRNA silencing through recruitment of TNRC6/GW182 and shows competition among silencing pathways.

This study identifies RIF1 as a phosphopeptide-binding protein that interacts with phosphorylated 53BP1 epitopes to facilitate DNA repair and modulate shieldin recruitment.