Author

D Holthaus

University Hospital Schleswig-HolsteinORCID 0000-0002-7012-5605Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Björn KonukiewitziD· 1 shared Christoph RogmansiD· 1 shared Dirk BauerschlagiD· 1 shared Franziska KellersiD· 1 shared Hauke S. BuschiD· 1 shared Huy Duc LeiD· 1 shared İbrahim AlkatoutiD· 1 shared Jörg Paul WeimeriD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Björn KonukiewitzORCID

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1 paper

Recent·Most cited

Cancer BiologyJCO Precision OncologyPeer-reviewedSep 1, 2026

Organoids serve as viable in vitro model for functional precision medicine for mesonephric-like adenocarcinoma of the ovary

D Holthaus, Huy Duc Le, Laura Matzner…·Nina Hedemann

The paper demonstrates that ovarian cancer organoids derived from mesonephric-like adenocarcinoma can be used for functional precision medicine, showing sensitivity to binimetinib and resistance to standard chemotherapeutics.

DOI 10.1200/po-26-00661

humanbulk RNA-seq

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