Author

Irina A. Okkelman

Ghent UniversityORCID 0000-0002-7014-6887Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:imaging· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1

Frequent Co-Authors

Ruslan I. DmitrieviD· 2 shared Sergey M. BorisoviD· 2 shared Angela C. DebruyneiD· 1 shared Austin E.Y.T. LefebvreiD· 1 shared Bert DevriendtiD· 1 shared Dauwe BulckaeniD· 1 shared Hang ZhouiD· 1 shared Linglong CheniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersPharmacology & Toxicology

Ruslan I. DmitrievORCID

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2 papers

Recent·Most cited

Electrically Enhanced Intraperitoneal Drug Delivery Resolved by Fluorescence Lifetime Imaging Microscopy

Nidda Saeed, Irina A. Okkelman, Sergey M. Borisov, Dauwe Bulckaen, Ruslan I. Dmitriev, Wim P Ceelen

This study evaluates electrically enhanced intraperitoneal drug delivery using nanoparticles and fluorescence lifetime imaging microscopy to track drug penetration and intracellular release.

bioRxiv · Oct 30, 2026 · PreprintPharmacology & Toxicology

Fluorescence Lifetime Imaging Microscopy (FLIM) visualizes internalization and biological impact of nanoplastics in live intestinal organoids

Irina A. Okkelman, Hang Zhou, Sergey M. Borisov, Angela C. Debruyne, Austin E.Y.T. Lefebvre, Marcelo Zoccoler, Linglong Chen, Bert Devriendt, Ruslan I. Dmitriev

This paper uses FLIM to study nanoplastic interactions and effects in intestinal organoids, finding species-specific uptake and disruptions in mitochondrial function and inflammation.

Light Science & Applications · Aug 12, 2025Peer-reviewedPharmacology & Toxicology