Transcription Factor Co-Expression Mediates Lineage Priming for Embryonic and Extra-Embryonic Differentiation
Alba Redó Riveiro, Jasmina Al-Mousawi, Madeleine Linneberg-Agerholm, Martin Proks, Marta Perera, Nazmus Salehin, Joshua M. Brickman
The paper identifies ESCs co-expressing GATA6 and SOX2, showing their cooperative DNA binding in enhancers and role in lineage priming for embryonic and extra-embryonic differentiation.
Stem Cell Reports · Jan 11, 2024Peer-reviewedDevelopmental Biology