Synthetic BiologybioRxivPreprint
Efficient in vitro refactoring and biosynthetic gene cluster amplification for the overproduction and accelerated discovery of anticancer thioamitides
Javier Santos‐Aberturas, Luca Frattaruolo, Eleonora Tassinari…·Andrew W. Truman
The paper describes methods to enhance thioalbamide production by refactoring its biosynthetic gene cluster and identifies a related compound with anticancer activity.
DOI 10.64898/2026.01.07.698260