Javier Santos‐Aberturas

Efficient in vitro refactoring and biosynthetic gene cluster amplification for the overproduction and accelerated discovery of anticancer thioamitides

The paper describes methods to enhance thioalbamide production by refactoring its biosynthetic gene cluster and identifies a related compound with anticancer activity.

Discovery of lydiamycin A biosynthetic gene cluster in the plant pathogen Rhodococcus fascians guides structural revision and identification of molecular target

The paper identifies a biosynthetic gene cluster in Rhodococcus fascians that produces lydiamycin A, a novel HPS-containing macrocyclic pentapeptide with antibacterial activity against peptide deformylase.

Understanding the biosynthesis, metabolic regulation, and anti-phytopathogen activity of 3,7-dihydroxytropolone in Pseudomonas spp.

This study identifies 3,7-dihydroxytropolone as a new antimicrobial compound produced by Pseudomonas, revealing its biosynthesis pathway and ecological relevance.

Chlamydomonas reinhardtii exhibits stress memory in the accumulation of triacylglycerols induced by nitrogen deprivation.

This study shows that Chlamydomonas reinhardtii exhibits stress memory in triacylglycerol accumulation after repeated nitrogen deprivation.