Author

Assunta Maria Casale

Istituto PasteurORCID 0000-0002-7025-7368Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:Drosophila· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Lucia PiacentiniiD· 3 shared Ugo CappucciiD· 3 shared Laura FantiiD· 2 shared Angela Alessandra Alagia· 1 shared Fabrizia NoroiD· 1 shared Federico AnsaloniiD· 1 shared Francesca PersichettiiD· 1 shared Francesco LiguoriiD· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersGenetics

Lucia PiacentiniORCID

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3 papers

Recent·Most cited

NeuroscienceiSciencePeer-reviewedDec 28, 2021

Transposable Element activation promotes neurodegeneration in a Drosophila model of Huntington's disease

Assunta Maria Casale, Francesco Liguori, Federico Ansaloni…·Lucia Piacentini

This study shows that transposable element activation contributes to neurodegeneration in a Drosophila Huntington's disease model and can be inhibited to rescue neurodegeneration and extend lifespan.

31 citations

Drosophilaexperimental assay

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GeneticsScientific ReportsPeer-reviewedMar 13, 2019

Heterochromatin protein 1 (HP1) is intrinsically required for post-transcriptional regulation of Drosophila Germline Stem Cell (GSC) maintenance

Assunta Maria Casale, Ugo Cappucci, Laura Fanti, Lucia Piacentini

This study shows HP1 is required for GSC self-renewal and differentiation by stabilizing key transcripts in Drosophila.

27 citations

Drosophilaexperimental assay

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GeneticsbioRxivPreprintSep 21, 2018

Survival protection mechanisms and genetic variability induction after stress: two sides of the same Hsp70 coin

Ugo Cappucci, Fabrizia Noro, Assunta Maria Casale…·Sergio Pimpinelli

This study shows that heat shock stress activates transposon expression by disrupting piRNA biogenesis through Hsp70's interaction with the Hsc70-Hsp90 complex in Drosophila.

DOI 10.1101/423210

DrosophilaDNA methylation

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