Katalina Bobowik

Impact of Rare and Common Genetic Variation on Cell Type-Specific Gene Expression

Single-cell eQTL mapping in 5.4 million PBMCs from 1,925 individuals with matched WGS finds common-variant eQTLs for 83% and rare-variant signals for 47% of 21,404 genes.

Tandem repeat variation shapes immune cell type-specific gene expression

The paper identifies immune cell type-specific gene expression regulated by tandem repeats using multi-omics data from large cohorts.

The whole blood microbiome of Indonesians reveals translocated and pathogenic microbiota

The paper analyzes RNA-seq data from whole blood of Indonesians to identify pathogens, finding Flaviviridae and Plasmodium as predominant, with distinct microbiome profiles compared to Mali and UK cohorts.

Transcriptomic profiles of Plasmodium falciparum and Plasmodium vivax-infected individuals in Indonesia

This study compares transcriptomic responses to Plasmodium falciparum and P. vivax infections in Indonesian patients to African and South American studies, finding shared and unique pathways.

Genome-wide DNA methylation and gene expression patterns reflect genetic ancestry and environmental differences across the Indonesian archipelago

The paper analyzes DNA methylation and gene expression in Indonesian populations to show genetic ancestry, environmental influences, and immune-related differences across regions.