Safarina G. Malik

A Global Atlas of Immune Alleles Reveals Health-Relevant Variation Across Groups

The paper presents GAIA, a global atlas of immune alleles, showing that underrepresented groups have more diverse alleles needed for vaccine design than Northwest European groups.

Rapid convergence toward an agriculturalist regulatory landscape following lifestyle transition in Bornean hunter-gatherers

This study shows that a recent lifestyle shift to agriculture in Bornean Punan people rapidly alters their transcriptome and DNA methylation, resembling agriculturalists more than their foraging relatives.

Ancestral and environmental diversity shape the immune landscape in Indonesia

This study identifies eQTLs and environmental influences on immune cell diversity in Indonesian populations, highlighting the role of ancestry and environment in shaping immunity.

From sporulation to village differentiation: the shaping of the social microbiome over rural-to-urban lifestyle transition in Indonesia

The paper presents a gut microbiome dataset from Indonesia, revealing novel species and subspecies linked to rural-to-urban lifestyle transitions and showing that community-level diet differences drive microbiome divergence.

Profiling genetically driven alternative splicing across the Indonesian Archipelago

The paper analyzes alternative splicing variation across 115 Indonesian samples to identify genetic variants influencing splicing, finding over 1,000 differential splicing events and 6,000 sQTLs with some ancestry-specific effects.

The whole blood microbiome of Indonesians reveals translocated and pathogenic microbiota

The paper analyzes RNA-seq data from whole blood of Indonesians to identify pathogens, finding Flaviviridae and Plasmodium as predominant, with distinct microbiome profiles compared to Mali and UK cohorts.

Maternal biomarker patterns for metabolism and inflammation in pregnancy are influenced by multiple micronutrient supplementation and associated with childrens’s biomarker patterns and nutritional status at 9-12 years of age in Lombok, Indonesia

This study examines how maternal biomarkers for metabolism and inflammation during pregnancy, influenced by multiple micronutrient supplementation, are linked to children's biomarker patterns and nutritional status at 9-12 years old in Lombok, Indonesia.