Abby S. Primack

This study characterizes the nervous system of Hydra vulgaris using scRNA-seq, identifying 15 neuron subtypes, mapping their spatial distribution, and exploring regulatory mechanisms through ATAC-seq and trajectory inference.

This study uses cell-type specific imaging in Hydra to show that neurons differentiate terminally before re-establishing functional neural circuits during regeneration.

This study generates new Hydra genomes and transcriptomic resources to uncover conserved transcriptional regulatory mechanisms in cnidarians.

This study identifies two distinct neuronal networks in Hydra vulgaris that coordinate mechanosensory responses, revealing how sensory information is processed in a radially symmetric nervous system.

This study maps stem cell differentiation trajectories in Hydra using single-cell transcriptomics, revealing shared progenitor states for neurons and gland cells and creating a gene expression map of the nervous system.