ImmunologybioRxivPreprint
Pathogenicity of autoreactive TH17 cells is modulated by the TRPM7 kinase
Katharina Jacob, Anna S. Thomann, Anna Madlmayr…·Susanna Zierler
This study shows TRPM7 kinase activity modulates pathogenic TH17 cell differentiation and function, with reduced TRPM7 activity leading to milder EAE and increased Tregs in mice.