Distinct specific interactions of the UapA transporter with membrane lipids are critical for dimerization, ER-exit and function
Anezia Kourkoulou, Pothos Grevias, George Lambrinidis, Euan Pyle, Mariangela Dionysopoulou, Argyris Politis, Emmanuel Mikros, Bernadette Byrne, George Diallinas
This paper identifies lipid interactions critical for UapA dimerization and function, and shows how mutations can restore these interactions in a mammalian transporter.
bioRxiv · Jul 22, 2019 · PreprintGenetics